Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division dynamin-related GTPase (DRP1) and mitochondrial division dynamin I (Dnm1). Mdivi-1 inhibits apoptosis by inhibiting mitochondrial outer membrane permeabilization. Mdivi-1 is the first selective inhibitor of mitochondrial division dynamins. Mdivi-1 represents a class of therapeutics for stroke, myocardial infarction, and neurodegenerative diseases.

Product information

CAS Number: 338967-87-6

Molecular Weight: 353.22

Formula: C15H10Cl2N2O2S

Synonym:

Mdivi 1

Mitochondrial division inhibitor 1

Chemical Name: 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

Smiles: COC1=CC(=C(Cl)C=C1Cl)N1C(=O)C2=CC=CC=C2NC1=S

InChiKey: NZJKEVWTYMOYOR-UHFFFAOYSA-N

InChi: InChI=1S/C15H10Cl2N2O2S/c1-21-13-7-12(9(16)6-10(13)17)19-14(20)8-4-2-3-5-11(8)18-15(19)22/h2-7H,1H3,(H,18,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.