Septin 8 (I203) Polyclonal Antibody

Catalogue Numbers: BS3938-50, BS3938-100

Sizes: 50µl, 100µl

Alternative Name: Septin-8; SEPT8; KIAA0202

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q92599

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 8 is a 508 amino acid protein that is expressed in the brain, cardiovascular regions, prostate, testis and ovary. Septin 8 interacts with both Septin 5 and cell division cycle related-1 (CDCrel-1). Septin 8 may play an important role in the functional regulation of hPFTAIRE1, a member of the Cdc2-related kinase family that is localized in cytoplasm. Septin 8, Septin 4 and Septin 5 surround α-granules, implicating these three septins as components of the septin complex in platelets and contributing to platelet biology.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Septin 8 (I203) polyclonal antibody detects endogenous levels of Septin 8 protein.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Septin 8 (I203) pAb at 1:1000 dilution
Lane 1: The Brain tissue lysate of Mouse(10ug)
Lane 2: The Brain tissue lysate of Rat(10ug)
Lane 3: PC3 whole cell lysate(40ug)
Lane 4: A549 whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 178-220 of Human Septin 8.

Conjugate: Unconjugated

Modification: Unmodified