AIF1 Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70353-60, E-AB-70353-120, E-AB-70353-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: AIF1

Target Synonym: AIF 1; AIF-1; Aif1; AIF1 protein; AIF1; Allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; allograft inflammatory factor-1 splice variant Hara-1; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Interferon responsive transcript 1; interferon responsive transcript factor 1; Ionized calcium binding adapter molecule 1; Ionized calcium-binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein g1

Research Areas: Cancer, Cell Biology, Metabolism, Immunology, Neuroscience

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Monoclonal

Clone No.: 5G4E7

UNIProt ID: O70200

Background: This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Concentration: 1.4 mg/mL

Immunogen: Recombinant protein corresponding to Mouse IBA-1

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:200-1:800

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only