GCG Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70318-60, E-AB-70318-120, E-AB-70318-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GCG

Target Synonym: GCG; GLP 2; GLP1; GLP2; glucagon; GRPP; Glucagon like peptide 1; GRPP Oxyntomodulin; OXM; Proglucagon

Research Areas: Cancer, Metabolism, Developmental Biology, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse, Rat

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P55095,P06883

Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Concentration: 1 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Glucagon

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:500-1:1000, IF 1:200-1:500

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only