RNase Z2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7054-50, ES7054-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Alternate Name: ELAC2; HPC2; Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human ELAC2. AA range:161-210

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 60528

Human SWISS Prot NO: Q9BQ52

Subcellular Location: Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Nucleus. Mainly mitochondrial.

Research Use Only