Insulin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8775-50, ES8775-100

Citations, Manuals and MSDS Available upon request.

Background: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

Alternate Name: Insulin [Cleaved into: Insulin B chain; Insulin A chain]

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic peptide from human protein at AA range: 30-70

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 3630

Human SWISS Prot NO: P01308

Subcellular Location: Secreted

Research Use Only