Oteracil potassium is an antagonist of urate oxidase. It is used to induce hyperuricemia in mice.

Product information

CAS Number: 2207-75-2

Molecular Weight: 195.17

Formula: C4H2KN3O4

Synonym:

Potassium azaorotate

Potassium otastat

Potassium oxonate

Chemical Name: 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid potassium

Smiles: [K+].[O-]C(=O)C1N=C(O)N=C(O)N=1

InChiKey: IAPCTXZQXAVYNG-UHFFFAOYSA-M

InChi: InChI=1S/C4H3N3O4.K/c8-2(9)1-5-3(10)7-4(11)6-1;/h(H,8,9)(H2,5,6,7,10,11);/q;+1/p-1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 9.09 mg/mL (46.57 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Shirasaka T, et al. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res. 1993 Sep 1;53(17):4004-9.
2. Eraranta A, et al. Oxonic acid-induced hyperuricemia elevates plasma aldosterone in experimental renal insufficiency. J Hypertens. 2008 Aug;26(8):1661-8.

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