Hydroxy-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 112724-27-3

Molecular Weight: 214.24

Formula: C6H14O6S

Synonym:

Upali Weersooriya, et al. Process for preparing isethionate ethoxylates. WO9529144A1

Chemical Name: 2-[2-(2-hydroxyethoxy)ethoxy]ethane-1-sulfonic acid

Smiles: OCCOCCOCCS(O)(=O)=O

InChiKey: DBAKPINNORMQCO-UHFFFAOYSA-N

InChi: InChI=1S/C6H14O6S/c7-1-2-11-3-4-12-5-6-13(8,9)10/h7H,1-6H2,(H,8,9,10)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.