VE-Cadherin Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22244-60, E-AB-22244-120, E-AB-22244-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: VE-Cadherin

Target Synonym: 7B 4; 7B4; 7B4 antigen; CADH5; Cadherin 5; Cadherin 5 type 2; Cadherin 5; type 2 (vascular endothelium); Cadherin 5; type 2; VE cadherin (vascular epithelium); cadherin; vascular endothelial; cadherin; vascular endothelial; 1; Cadherin-5; Cadherin5; CD 144; CD144; CD144 antigen; CDH 5; CDH5; CDH5 protein; Endothelial specific cadherin; FLJ17376; OTTHUMP00000174777; Vascular endothelial cadherin; Vascular epithelium cadherin; VE Cad; VE-cadherin; VEC

Research Areas: Cancer, Cardiovascular, Signal Transduction

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human, Mouse, Rat

Application: IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:8E5

UNIProt ID: P33151

Background: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide of VE-Cadherin

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification Method: Protein A purification

Dilution: IHC 1:100-200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only