Musashi 1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90897-50, BS90897-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q07954(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IHC, IP, , FC

All Applications: WB:1:1000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:200

Background: Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Musashi 1 polyclonal antibody detects endogenous levels of Musashi 1 protein.

Bioworld Molecular Weight: 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining Musashi 1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining Musashi 1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: LRP-1, A2MR, APOER, CD91, LRP1, Msi 1, Msi1, MSI1H, Musashi homolog 1, Musashi-1, Musashi1, RNA binding protein Musashi homolog 1, RNA-binding protein Musashi homolog 1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified